Fibroblast Treatment

Fibroblasts, which are the basic cells of connective tissue, undertake extremely important tasks in the body. It is the task of fibroblasts to ensure the production of elastin and collagen, which are of great importance for the skin and provide shine and elasticity to the skin. Another task of fibroblasts is to activate the organism’s wound treatment system in case of any damage to the skin.

What is a Fibroblast?

The skin may develop sagging, lines, wrinkles and tissue deformities due to an unhealthy diet, harmful lifestyle habits, side effects of various medications, aging, accidents and many other reasons. Although this situation does not cause serious functional problems, it may cause discontent of the person by creating an unaesthetic appearance. Fibroblast therapy, which is frequently applied to eliminate this condition, is one of the methods that have increased in popularity in recent years.

Fibroblast cells begin to decrease in every person after the age of 25. The natural result of this situation is that wrinkles and sagging begin to form. Within the scope of fibroblast therapy, fibroblast injection is performed and collagen and elastin production in the injection area is triggered to be reactivated. Collagen and elastin fibers then begin to regenerate. Since the task of collagen and elastin fibers is to provide skin elasticity and resistance, a strong anti-aging effect is created on the skin. In this way, it is aimed to prevent aging of the skin and to provide effects such as skin tightening and rejuvenation.

Why is Fibroblast Made?

Fibroblasts, which are predominantly seen in connective tissue structure, have many different roles in the skin. The most important role of fibroblasts is the production of glycosaminoglycans such as elastin, collagen proteins and hyaluronic acid, which are very important for the skin and provide elasticity and shine to the skin.

When the fibroblasts in the skin decrease due to various reasons and the building blocks produced by the cells decrease, signs of aging occur due to structural disorders in the skin. Fibroblast cells isolated and cultured from the patient’s own skin tissue produce the proteins and growth factors needed by the skin.

Thanks to their anti-inflammatory properties, fibroblasts suppress inflammation caused by any cause. Fibroblasts, which reduce the signs of aging on the skin, also play an important role in wound healing.

The areas of use of fibroblast therapy for aesthetic purposes can be listed as follows:

  • Lip plumping,
  • Treatment of skin dimples,
  • Treatment of skin cracks,
  • Treatment of lines formed on the lips,
  • Wrinkle treatment,
  • Treatment of tissue losses caused by an accident or childbirth,
  • Treatment of chickenpox and acne scars,
  • Treatment of wounds that do not close due to chronic ulcers.

The process of elastin and collagen production is triggered in the area where young and fresh fibroblasts injected at the application site are applied for the treatment of the aforementioned problems. A strong anti-aging effect appears on the skin. As a result, a tightening and rejuvenation effect is achieved on the skin.

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How is Fibroblast Applied?

Fibroblast treatment is a popular procedure that can be applied as an alternative to various medical aesthetic and surgical aesthetic procedures in order to improve and tighten the appearance of the skin. Although fibroblast therapy is one of the newly applied treatments, its popularity is gradually increasing.

Local anesthesia is performed on the patient to be treated with fibroblast. A tissue sample with a diameter of about 3 mm is taken by punch biopsy. The tissue can be taken from behind the ear, through the arm or from the groin area, in other words, from areas that do not see the sun and do not spoil the aesthetic appearance. The patient does not feel pain or soreness when performing a punch biopsy.

The biopsy sample obtained by punch biopsy is engraved into the kit provided by Stembio Laboratories. Jul.100.jul.100.jul.100.jul.100.jul. It should be sent to the laboratory by cold chain within 24 hours at the most. The tissue, which is called intra-dermal, is subjected to various procedures in a laboratory environment that works under cGMP conditions and has been granted production permission by the Ministry of Health. Thus, the fibroblast production process is started. at the end of the 4-week period, a total of 100 million cells ready for transplantation are reached.

After detailed quality control and characterization studies, the presentation of the final product, which is prepared and made injectable, takes place in sterile vials. The application is made in the form of multiple injections using the smallest 26G injector and by mesotherapy method.

Forehead, hands, chin, Decollete area, eye and lip area can be considered among the main areas of use of fibroblast treatment. Fibroblast treatment is applied in 3-dose cycles with intervals of 2 to 6 weeks depending on the decision made by the doctor on the patient’s specific Deciency. An average of 30 million fibroblast cells are used in each application. Fibroblast cells are frozen and when desired, 2. and 3. it is stored in nitrogen tanks in the vapor phase in the -196 stream at the relevant center for use in the form of doses.

Fibroblast therapy has the property of being a long-term treatment. On the other hand, this period may vary depending on factors such as the patient’s quality of life, stress factor in his life, amount of water consumption, genetic structure, skin structure, age, facial use habits, UV, smoking and alcohol use habits.

After fibroblast application, the patient should take care not to be exposed to too much sunlight. Making a cold compress with the help of an ice battery on the day of application may be beneficial.

Who Is Fibroblast Suitable For?

Fibroblast treatment is a procedure that can be applied to all women and men who want to rejuvenate the skin tissue due to various problems found on the skin or to postpone the deformations that occur over time on the skin tissue. Since the person’s own cells are used within the scope of fibroblast treatment, that is, it is an autologous treatment, there is no risk of allergies and the application can be performed safely. On the other hand, in order for the desired skin rejuvenation effect to be achieved at the highest level, the person’s age range of 30-40 December may become a beneficial factor.

What are the Advantages of Fibroblast Treatment?

After fibroblasts are injected into the skin, the production of structural proteins such as collagen, elastin and hyaluronic acid is triggered in the area where young and fresh fibroblasts are applied. Thanks to this, the skin begins to regain the shine and elasticity that it has lost. Usually, improvement becomes noticeable after the second injection. It is considered an extremely important advantage that the duration of action and persistence of fibroblasts are higher than in other applications.

Fibroblast therapy is an autologous treatment procedure. Since it is a natural treatment method, there is no risk of causing an allergic reaction. In addition, toxic, carcinogenic and teratogenic effects do not occur.

When Is the Fibroblast Effect Seen?

The basic points to be considered after many medical aesthetic procedures also apply to the process after fibroblast treatment. After fibroblast treatment is applied, protecting the skin from the sun, paying attention to the care and hygiene of the donor area are among the most important issues to be considered. Therefore, it is necessary to take care that these areas are not touched for 3 days after fibroblast treatment. In the same way, care should be taken to avoid perfume and cosmetic contact with both the donor area and the application area for 3 days. Due to the fact that fibroblast is a treatment applied by micro injection method, it is possible to experience short-term effects such as redness, bruising or swelling at the injection site after the procedure. Such side effects resolve spontaneously 1-2 hours after the procedure.

The effect of fibroblast treatment is usually 2. although it starts to be noticed after the injection, it takes an average of 4 to 6 weeks for it to become noticeable.

Frequently Asked Questions About Fibroblasts

How do fibroblast cells ensure the regeneration of the skin?

Fibroblasts are seen predominately in the connective tissue structure. Its most important tasks are the production of glycosaminoglycans such as elastin, collagen proteins and hyaluronic acid, which are very beneficial for skin health and make the skin more flexible and shiny. Due to various reasons, when the fibroblasts in the skin and the building blocks produced by cells decrease, structural disorders in the skin, accordingly, signs of aging occur. Fibroblast cells, which are isolated from the patient’s own tissue and cultured, take over the production of growth factors with the proteins needed by the skin. When young and fresh fibroblasts trigger the production of elastin and collagen, it is possible to achieve a tightening and rejuvenation effect on the skin.

Do fibroblast cells help rejuvenate the skin?

Fibroblast cells are located in the middle layer of the skin and contribute to the production of collagen and elastin fibers, which provide elasticity to the skin. Thanks to this, they help rejuvenate the skin. Fibroblasts also contribute to the production of various substances that provide skin repair. Thanks to these properties, fibroblast cells take on an important task on the way to skin reconstruction and healing of skin damage. For this purpose, fibroblast cells are often used in skin rejuvenation treatments.

What is it that fibroblast cells produce collagen?

Fibroblasts in the organism lose their ability to produce elastin and collagen over time. Fibroblasts, especially in the sun-exposed part of the skin, deteriorate as a result of effects such as radioactivity in sunlight, and their number decreases over time. Skin vitality disappears, collapse and sagging appear, wrinkles occur. To eliminate these negative effects, fibroblast cells taken from a person are applied to the skin. Fibroblasts produce collagen and elastin substances that are critical for skin health and appearance. Thus, the possibility of giving softness, brightness and elasticity to the skin is also achieved.

How long does fibroblast treatment take?

How long the fibroblast treatment will take may vary depending on the size of the area to be treated, the goal of the treatment, the patient’s needs and expectations. The healing process continues for 6 to 8 weeks following fibroblast treatment. Fibroblast cells, which divide to repair skin problems, naturally begin to produce new collagen in this process. Thus, the effects of the treatment are strengthened. It is usually administered in the form of 3-dose cycles at December intervals of 2 to 6 weeks. Although an average of 3 months is needed to see the results of treatment, the complete results of the fibroblast procedure can typically last up to a 3-year period.

By what methods is fibroblast treatment performed?

Fibroblast treatment is performed under local anesthesia. After a 3mm diameter tissue sample is taken with a punch biopsy, it is sent to the laboratory in a special kit within a maximum of 24 hours. The tissue, called intradermal, is subjected to some procedures in a laboratory environment that works under cGMP conditions and has been granted a production permit by the Ministry of Health. Thus, fibroblast production begins. Fibroblasts contained in sterile vials can be applied in the form of multiple injections with a minimum 26G injector and mesotherapy method. Fibroblast is a painless and painless treatment.

How often is fibroblast treatment performed?

Fibroblast treatment is usually performed at intervals ranging from 2 to 6 weeks and repeated 3 times. December Dec. How often fibroblast treatment will be applied is determined after making evaluations based on patient-specific needs, expectations, the scope of treatment, and many other different factors. as part of a 3-session treatment, between 20 and 40 million fibroblast cells are injected into the patient every session Decently. Although the duration of the appearance of the results to be obtained after the treatment may vary depending on the individual, they usually start to appear after the second session.

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